Under Debate: Psychiatric Medications
Medications are often prescribed to treat mental conditions, but are they all they’re cracked up to be? I’m Gabe Garza with your latest health news. Some researchers have raised concerns that …
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Seasonal Allergies: Which Medication is Right for You?
When your seasonal allergies are driving you crazy, all you want is relief. Here are the four types of medicine to consider. Antihistamines are drugs that reduce or block the chemicals …
When your seasonal allergies are driving you
crazy, all you want is relief. Here are the four types of medicine to consider. Antihistamines are drugs that reduce or block
the chemicals in our bodies that cause symptoms like itchy eyes and sneezing. Decongestants help relieve your stuffy nose. Nasal corticosteroids can help reduce nasal
inflammation. And immunotherapy involves taking small amounts
of the allergen that causes your symptoms. Though usually injected, some immunotherapy
meds (called sub-lingual) can be taken under the tongue. Whichever allergy medicine you choose, be
sure to ask your healthcare provider for guidance; and carefully follow the instructions on the
label.
Therapeutic Innovation Steven McCarroll
On the topic of therapeutic innovation, please welcome Dorothy and Milton Flier professor of biomedical science and genetics at Harvard Medical School, Steven McCarroll. Hi, I’m Steve. Several years ago, I …
On the topic of
therapeutic innovation, please welcome Dorothy
and Milton Flier professor of biomedical
science and genetics at Harvard Medical
School, Steven McCarroll. Hi, I’m Steve. Several years ago, I was given
a chance to start a lab here at Harvard Medical School. With that came a
chance to contribute to a scientific
ecosystem like no other in the world, a
discovery engine that works to transform
possibilities for human health. But this engine is
powered by people, people like you just heard in Rachel– brilliant, passionate
students, postdocs, residents, fellows, who come
and trained here to unravel the
mysteries of biology and to alter the course
of human disease. This is an image from
one story of so many from that kind of work here. Schizophrenia is a
devastating illness, long in need of biological
insight and innovative therapies. The medical treatments used
to treat schizophrenia today have hardly evolved
from drugs that were used in the
1960s, drugs that treat a single symptom, while
leaving the underlying disease untouched, because its
mechanisms are unknown. Enter Aswin Sekar,
an MD PhD student at Harvard Medical School. Aswin invented a new way
of analyzing human genome data, a combination of molecular
biology experiments he did in the lab, statistical
approaches and computer algorithms he wrote, to make
forms of genetic variation that were previously
invisible visible to analysis. He then applied his approach
to genetic data that, from DNA that had
been contributed from tens of thousands
of schizophrenia patients from 30 countries
all over the world. Aswin’s analysis taught
us how the human genome exerts its strongest influence
at a population level on risk of schizophrenia. He showed that
this effect arises from overactive forms of a gene
called complement component four, C4 for short. This was surprising,
because C4 was considered an immune protein. More surprisingly,
as shown here, we found the C4 protein
present at synapses, the place where neurons contact other
neurons in the nervous system. Nearby, at HMS, Aswin
found both Mike Carroll, an expert on the biology
of the complement system, and Beth Stevens,
who had discovered that other related
complement proteins have a surprising other job in
the brain, where they act as molecular tags that
elicit the pruning or severing of connections
between nerve cells. Together, this team, including
also people in all three of our labs, showed that
the C4 genes do this also and that these overactive
forms of the C4 genes do this excessively. This team’s findings
advanced our understanding of schizophrenia in a
surprising direction. That knowledge,
we hope, will make it possible to develop new kinds
of therapies that might address the root causes of the illness. But this is just
one of many ways that new approaches and
technology platforms can be created and used to open
new channels in our ability to listen to human biology. You’re looking here at
a movie of another one, a technology we call drops seek. A long-standing need
in science and medicine had been to better capture the
biological information that’s present, but hidden
inside of tissues. We know the information
about disease processes must be locked up in
the molecular states of the individual
cells within tissues. But accessing this
information was challenging for a very long time. These two Harvard
Medical School postdocs, Evan Macosko and Allon
Klein, conceived and led efforts to develop technologies
for analyzing tissues at the single cell
level by encapsulating each individual cell
in a tiny water droplet to have its molecules bar coded
with DNA for its own precision molecular analysis. You can see from this movie the
speed at which individual cells can be packaged and bar coded
and processed for analysis. This allows single cell
sequencing of tens of thousands of individual cells at once. And they organized
interdisciplinary teams across the Harvard physics
department and the Broad Institute to
actualize this vision at the level of droplet fluid
as physics and data science. Today, this technology
is helping scientists around the world to identify
all of the cell types in the human body, to learn
which genes are expressed in each cell population, and
to identify the vulnerable cell populations in many diseases. This is my sister, who
last year benefited from life-saving
experimental medicine in a clinical
trial for lymphoma. Many of you in the
audience may know what it’s like to
experience firsthand the transformative power
of experimental medicine in a tangible way. The experience induces
profound gratitude, and also awe at the
promises and possibilities that biomedical research gives
to people and their families. For all of us who
do such research, such an experience also
enhances a sense of urgency about getting everything
done as quickly as we can. There is no waiting for
the science to get there. We need to drive it forward
and share it exuberantly, so that advances
can benefit people we know and love here and now. Thank you very much.
Four Inversion Table Exercises for Back Pain – Therapeutic Massage Specialist endorses Teeter
For spinal decompression I can’t say enough about the Teeter EP-960 table putting the spine in inversion, as you know with gravity we’re always locking down our spine and these discs …
For spinal decompression I can’t say enough about the Teeter EP-960 table putting the spine in inversion, as you know with
gravity we’re always locking down our spine and these discs in here that
cushion each vertebrae start to become, they start to become compressed
sometimes they’ll turn into a bulge and when you get fluid spilt out in that
spinal nerve it starts to cause a tethering of these nerve roots, so what we’re gonna be doing is we’re gonna doing some spinal decompression where we’re gonna
try to take pressure off each disc. As you know over time during the day you
lose about 3/4 of an inch in height just because there’s that much gravitational
forces compressing all these discs and by the time you’re in your 80s or 90s
you’ve probably lost about 2 inches in height and that’s just shows how much
this gets gets decompressed and at night they hydrate a little bit but when you
use the Teeter Inversion EP-960, what happens is you can actually decompress
the spine every day and pull interstitial fluid back into these discs
and what we know there’s even that one study that says that the herniated discs
can actually move back into place when we do spinal decompression. So what we’re gonna do is we’re gonna get Fran with the easy EZ-Lock for the leg piece
this is gonna scoot into the inversion machine and what Fran’s gonna do is
she’s gonna just – You want to watch as she locks that in make sure you hear it
clip in and she’s gonna slowly just use one arm and you’ll see how she can
control easy inversion on this machine now when you first do this you’re only
gonna go about thirty (degrees), Fran’s been doing this for months so she started out at
about thirty degrees of inversion she started one to two minutes and then she
worked up to doing it at five or six minutes at about forty five now at sixty
degrees of inversion so please work up to this place now in order for these
discs to hydrate and for fluid to get into the discs we need to add some
movement but before we do that if you remember the video we had this L4, L5 compression we had to drop that sacral base down if you remember the
lower body nerve video when the glutes weren’t working the QL which is locking
down these these spinal nerve roots was working overtime so a good exercise to
start once you’ve done the inversion. Fran, I just want you to do a
posterior pelvic tilt and as she’s doing that she’s taking that sacral base away
from that bulge herniation or rupture and she’s getting some fluid back in
here but mostly she’s decompressing the L5, S1, the sacral lumbar articulations
and stretching those ilio sacral ligaments. Now the other thing Fran’s
gonna do is she’s gonna rotate from side to side. Again motion is going to get
fluid back in those discs now we’ve got spinal decompression we’ve got motion
going on so we’re getting decompressed and we’re getting fluid we’re getting
hydration back in those discs and then if you remember Fran had a positive
Eden’s test she had a positive cost of clavicular test and she had a positive
Addison’s test so if she reaches back she’s stretching out her PEC minor what
happens when she stretches out her PEC minor she’s relaxing her rhomboids
what’s also happening because of the inversion table, the clavicles can
actually lift up off of that first rib to decompress the subclavius artery in
the brachial plexus of nerves the other thing I like to do is I sort of like to
add a small towel roll. Remember we’ve restored the normal cervical curve
Fran, so put this under your neck right in the middle of the neck so it
allows that remember that cervical curve that normal lordotic curve and now you
again we’re decompressing all the discs, she’s stretching out the pecs and the
last part friends gonna do giving her this you know just three to five minutes
she’s worked up to now she’s it like six minutes I want you to put your fingers
under your occiput Fran, now remember how the occiput was coming back because
of the forward neck posture now if you do a little chin tuck and you get into
the occiput what that does is that opens up pressure off that basal artery
and allows c1 to rotate more effectively over C2 so just hang for a little bit
Fran and now sometimes you just want to do nothing you just want to hang
there for a while again if you’re gonna do this, start at
about thirty degrees maybe one to two minutes build up over weeks and then the
most important thing i can say there’s a lot of precautions and contraindications
please check with your doctor read the instruction manual do not use an
inversion table especially if you have things like atherosclerosis if you have
things like hypertension if you have things like high blood pressure you’ve
got glaucoma there’s a whole list of things extra Hardware in your spine and
that could be counterproductive so please before you invest in any
inversion table please consult with your doctor to make sure it’s safe based on
your medical and clinical condition
Alexx Discusses His Frightening Health Scare | Ready to Love | Oprah Winfrey Network
Tommy: Ready to Love had some significant ups and downs in season one, but none was more concerning than the tragic news of Alex’s health at the end of the season. …
Tommy: Ready to Love had some significant ups and downs in season one, but none was more concerning than the tragic news of Alex’s health at the end of the season. Tommy: Right off the top I just want to address the fact that one of our most loved singles isn’t here with us tonight. Some of you might be aware that over the Thanksgiving holiday, Alex contracted a very rare flu virus which spread to his brain leaving him currently hospitalized. Tommy: Now, I know you all have been wondering what’s been happening with his recovery. Thankfully we can give you some answers because he’s here with me today. My man, Alex. Alexx: Hey. Tommy: How you doing bro? Alexx: Man. Tommy: Woo. Alexx: Good man. Tommy: It’s been a whirlwind hasn’t it? Alexx: Yeah it definitely has, man. It really has man. Tommy: Everybody everywhere I go, asking about you. They’re praying for you. And we never gave up on you brother. Alexx: Man I appreciate that I really, really do. I really do I just want to thank you especially and the network, Will Packer, Oprah. Just to have the support, the friendship, the love, the care, behind the tragic thing that happened to me. Tommy: Take me from that, take me from day one of what happened. Alexx: I was headed to work, you know I’m a truck driver. So I was headed to my truck. And just ended up regurgitating, you know what I’m saying. Ended up throwing up for no obscene reason. Well after that I called my sister and I remember nothing after that. Two months in the, two and a half months later I woke up in the hospital. Like what happened? And they was like, you died twice man. You were almost out of here man. You almost checked out. Tommy: Two and half months. Alexx: Two and a half months man. Tommy: What did they diagnose this as? Alexx: Influenza B, but it was a lot stronger than Influenza B. It went and hid in the brain stem. Tommy: The flu did. Alexx: Yes, it hid in the brainstem of my head and grew stronger. As it grew stronger it started breaking things down. Nerves and you know everything, it’s just everything, you know what I’m saying. That’s what shut my body down. So when I woke up I was like… Tommy: Moving up. Alexx: Right. It was ridiculous. Tommy: And that was two and a half months later. Alexx: Two and half months later. Tommy: How difficult has the recovery been? Alexx: It’s getting better. It’s definitely difficult. You know what I’m saying, you know coming from being bedridden and not being able to really move or talk or go to the bathroom. Do anything that you would normally do, you know what I’m saying, independently. Tommy: You also had to learn how to walk all over again. Alexx: Yes man, the whole nine. But hey man, I mean I’m blessed man. I’m here Tommy. I’m here man. Tommy: Have you felt the love that have come from the whole Ready to Love fans? Alexx: Oh my god man, have I. I mean it was so, just endearing just knowing that people had so much love. You know what I’m saying, just the people you see every day, you come in contact with. I mean just people I don’t even know. You know what I’m saying, they just have so much love and support for me. And I will never, ever forget that. Tommy: Your determination, I applaud you on it brother. Alexx: Thank you. Tommy: And just determined to live. Alexx: Yes man. Tommy: You know what I mean? Alexx: Yes. Tommy: And I think you got your priorities together, you know why you here. You know it was God. I’m proud of you, we going to continue to pray for you and pray that you go back and get to 100% if not even 110. Alexx: Yes sir. Tommy: Next time I see you you’re going to shake my hand and hurt my hand. Alexx: No you already know that. Hello again brother. Tommy: Oh man. Alexx: Yes sir. Tommy: Love you man. Alexx: Thank you man. Tommy: Still got a little grip. Alexx: Hey man a little bit, a little bit you know what I’m saying. Tommy: It’s coming. Alexx: It’s coming, hell yeah. Know what I’m saying, my man.
Yoga For Gut Health | 18 Min. Yoga Practice | Yoga With Adriene
– Hi everyone, welcome to Yoga With Adriene. I’m Adriene and this is Benji and today we have an awesome yoga for gut health, so hop into something comfy and let’s …
– Hi everyone,
welcome to Yoga With Adriene. I’m Adriene and this is Benji and today we have an
awesome yoga for gut health, so hop into something
comfy and let’s get started. (upbeat music) Alright, my sweet friends, let’s begin seated in a nice, cross-legged pose. We call this the
easy pose, Sukhasana, but it’s not necessarily
to mean that it’s easy, so just come on
down to the ground. If you need to lift the hips up or give yourself a little
pillow or something to sit on to help you sit up
tall versus rounding and collapsed in the spine. When we sit collapsed,
our internal organs get kind of smushed together, so
pause the video if you need to and find something to sit on so you can sit up nice and tall. Find a little lift from within. And then throughout regular
practice we’ll find more ease in the shape, alright? Thanks for being here,
let’s jump right in. Sit up nice and tall. Let your hands just gently rest on the knees or thighs,
wherever they fall naturally. If you feel comfortable,
close your eyes here as we just take a
second to tune in. Really utilizing and, I’m gonna say it, maximizing this time that
you’ve carved out for yourself. So, with targeted practices
we have to also remember that with yoga we’re
working with an understanding of a whole body and
that’s what we’re trying to grow is this whole body awareness, that it’s all connected
and when we’re talking or considering gut health, I think that’s an
important reminder. Alright, if you haven’t already, begin to bring your
attention to your breath. Notice if you’re
holding in your belly. See if you can soften there and if you’re
holding any other place, the jaw, the toes, even in
the hands or the shoulders, start to soften and relax,
come into the present moment. Right, it’s all connected. Then, together, I’ll invite us to
take the deepest breath you’ve taken all day.
Here we go, ready? Big inhale. And as you exhale, go
ahead and release it out through the mouth
with a little ha sound. Good, big inhale again. Exhale, ha sound. Relaxing the shoulders as you
breathe out, one more time. Here we go, big inhale. Lift your heart,
sit up nice and tall. And exhale, relax the
shoulders as you breathe out. Good, now bring
your hands to your belly. Inhale, breathe in. This time as you breathe in, think of this
directional breath, what we call directional breath. Your inhale goes down, you can feel your hands
actually move as you breathe in. And exhale, soften,
hands gently draw in, slight retraction
as you breathe out. Twice more like that,
here we go. Big inhale. Feel the belly expand,
heart lifts. Exhale, navel gently
retracts back to the spine. And one more time, inhale. And exhale. Excellent. Bring your
fingertips to your sides, plant the left
palm to the earth. Inhale, reach the
right arm all the way up. Big side body stretch. If you feel collapsed
in the belly, again, maybe lift the hips. We’ll work to find
that Upward Facing Dog or Cobra sensation in the heart. This lift through
the chest up so we can minimize the
collapse in the belly and then, when you’re ready, we’re gonna take it
all the way up and over just past the
front of your left knee. So you’re feeling a big stretch in your lower right
side of your back, sorry. And we’re feeling a massage or a little compression
in the left low belly. If the fingertips come
to the ground, let them. If not, just
reach, reach, reach. Great, inhale in. For your next exhale,
draw the chin to the chest. Good, inhale, just reverse,
come all the way back up. And exhale, right
fingertips to the earth. Great, second side.
Right hand to the earth. Inhale, first, come
out of the left sideways by reaching all the way up. Left fingertips to the sky. Inhale in. Exhale,
slowly take it up and over just
past your right knee, so going on a diagonal line. Creating space in
the left low back. Creating a little compression in the right low belly
and right oblique. Maybe you stay reaching here, maybe the fingertips
come to the ground. Breathe, breathe, breathe. Alright, listen carefully. Inhale to look forward.
Exhale, chin to chest, navel draws in,
hug the low ribs in. Sweet. Slowly reverse it,
come all the way back up, left hand reaches all
the way up towards the sky and we come back down,
fingertips to the earth. Alright, we’re gonna
uncross the ankles here. Just bring one foot
in front of the other. Let’s unify, let’s
bring the left heel in and then the right foot
in front just for starters. Then, here we go,
big inhale, palms face up, sweep up towards the sky,
lift from your waistline. So creating a long sensation
through the front body, just kind of grounding
sensation through the back body. Again, coming up
out of our organs a bit, finding that left
from the pelvic floor. Inhale in. Exhale,
dial your heart space towards your left knee.
So, twist to the left and then we’re gonna take it
down just like we did before. But this time both fingertips
coming towards the ground. Inhale to look forward, smile. Exhale, chin to chest,
round through. See if you can create a
little hollow body here. Navel draws in. Cool. Walk it through center,
get as low as you can. No need to go as low as me, but if you can get
forearms to the ground, great. Otherwise stay lifted. You can even come
forehead to the earth. And then walk it all
the way to the right. Inhale to look forward, smile. Exhale, chin to chest. Inhale to bring it
all the way back up. Reach for the sky. And exhale, fingertips float
down gently at your sides. Good, let’s switch. Right heel comes in,
left leg out. Here we go, big inhale,
reach for the sky. Beautiful, exhale from center. So, slowly twisting
to the right from here. Good, inhale in again. Exhale over to your
right nice and easy. And just check it out,
breathing deep. So really focusing on the sensations today
versus the shape. Really, always in yoga, but
really today so we can start to create more awareness. Well, a deeper
relationship with your guts. So many metaphors there. Okay, inhale, look forward. Exhale, chin to chest. Good, and then here we go,
walking through. Coming through center,
forearms, fingertips, forehead to the mat,
nice hip stretch here. So breathe deep,
breathe into your belly. And then keep this train moving. Let’s go all the way
over to the left, aw yeah. Inhale, look forward,
open the chest. Find extension.
Exhale, contract, navel draws in, chin tucks. Sweet, and then release
by bringing fingertips all the way up towards
the sky, big breath in. Exhale, fingertips float down. Awesome work. Alright, from here, we’re
gonna slowly come to a seat. So lean back on your bum. Bring your
knees up into the sky, bring your hands
behind your thighs. Loop the shoulders,
lift your heart. Inhale in, exhale, don’t think,
just breathe, lean back. Toes can stay on the ground. Inhale in.
Exhale, lift your heart. Shoulders drop and one
more time, big breath in. Send that breath down
into the belly, inhale. Exhale, maybe the shins lift. Good, try to keep
your elbows hugging in. So your shoulder blades
can wrap down and around. Down and around, yes. Inhale in again. Exhale, maybe you release the
fingertips, palms face up. Inhale in again. You never know, exhale, maybe
you straighten the legs. Lift your heart. Armpit chest lifting here,
heart’s lifting. Elbow creases towards
the sky for three, two. On the one, slowly release. Come through to all fours. Knees underneath the hips,
wrists underneath the shoulders. Just one Cat-Cow here, so drop
the belly, open the chest. Exhale, round through
the spine, chin to chest. Good, cross one
ankle over the other. You’re gonna paint
your yoga mat with your mat as you come back all
the way through to a seat and then all the
way to your back. And when you land on your back,
go ahead and center yourself on your yoga
mat if you have one. And then I’ll invite us all to
hug the knees into the chest. So I’ll meet you here. You can take a
couple breaths here to rock gently side to side. Little low back love here as
you scoop the tailbone up. Keep your shoulders
relaxed, elbows. Lots of awareness and the elbows
drawing down perhaps here. Little awareness in the feet. Inhale in. Exhale, draw
your nose towards your knees. Doesn’t matter if
your nose comes close to your knees at all. Just find that intention, so really squeezing,
squeezing and squeezing. Option to grab the outer edges of the feet,
keep breathing here. And then when
you’re ready, slowly release. Hold onto your right shin, kick your left
leg all the way out. Inhale in deeply here. Exhale, peel your nose
up towards your right knee. Keep breathing, strong
left leg, flex your left toes. Good, and then slowly release. We’re gonna switch,
send the right leg out, bring the left knee up,
inhale in. Exhale, nose toward the knee. Breathe here, strong right leg. Shoulders relaxed,
skin in the face soft. Good, slowly release. Switch, right leg comes back up. Inhale in. Exhale,
right knee crosses over the left side of the body. You can even shift
your hips to the right side of your mat as you
come into this Supine Twist. Send your right arm out long,
use the palm of your left hand to gently comb the
outer edge of your right thigh that IT band all the way down.
The power of touch. And maybe gently
turn onto your right ear, find that directional breath here breathing
down to the belly. You gotta bring the breath,
you got this. The more depth of breath you
can find in this practice, the more benefits I think
you’re going to experience. So think of it that way,
my darling. When you’re ready, let’s come back
through to center and switch. Take it to the other side,
extending the right leg out, lifting the left
knee up and taking it over into your Supine Twist. Again, option to
bring the hips over towards the left side of the mat. Then we’ll extend
through the left arm. Maybe you come onto
your left ear, breathe deep. Oh, my mid-back
is a bit tight today. And then use your right hand to gently comb the outer
edge of your left thigh down. Nice, deep, loving
breaths here, you got this. Notice how the
breath, in particular, the depth of breath, notice how that can
change your experience and the way you
feel in this shape. Even just three deep breaths
can change it, change it all. I can even hear my
stomach talking in this shape. It’s working! Okay, one more breath. Come back to center,
hug both knees up into the chest once again. This time we’re gonna
take them wide, nice and wide. Knees wide, squeezing, lifting,
breathing into the belly. If you wanna take a
Happy Baby here, you can. Grab the outer edges of
the feet or the inner arches, kick the soles of the
feet up towards the sky. Deep breath in, long
breath out as you reach your tailbone towards
the front edge of your mat. Nice, and then slowly bring
the soles of the feet down to the ground,
hands come to the earth to walk your heels up
towards your sits bones. Feet are nice and hip-width
apart, toes pointing forward. Inhale to lift the
hip points up high. Breathe into the belly, crawl
the shoulder blades down towards your heels and
exhale slowly to lower. Good. From here, we’re
gonna walk the feet as wide as the yoga mat, knees come into touch, soften through
the bowl of the pelvis and bring your
hands to your belly. Slow and steady clockwise
circles rubbing the belly nice and slow, breathing deep. If you have not caught a nice,
deep breath yet, do it for yourself now. And then stop, pause,
relax everything here. Knees are kissing
towards each other, elbows are relaxed on the
ground, shoulders are relaxed. Close your eyes and just
listen, listen to your breath. Learn to take more time to listen to your guts,
your intuition. It’s all connected. And then just pay attention,
notice what came up here. There’s no right or wrong. We’re gonna open the knees wide,
lift the heels, lift the feet. Cross one ankle over the other, grab the outer edges of
the feet or your big toes. We’re gonna rock and
roll up and down the length of the spine here. Should feel really good. Come back up to that nice,
comfortable seat. Voice cracked. Hands on the knees, we’re gonna finish
with a coffee grinder. Here we go, inhale,
smoothing the heart forward. Exhale, round the spine,
send it back. Inhale, forward.
Exhale, round the back, getting the juices flowing here. So, some of you
may not know (laughs) what those old-fashion
coffee grinders look like, but they look like this. And you turn the
handle and you grind the coffee down below and then
you open the little drawer and your coffee’s there for you. If you do know
what I’m talking about, awesome, if not,
you can imagine it. Reverse your circle. Sync up with your breath. Alright, let your
circle get smaller and smaller and smaller here. Smaller and smaller and
smaller and smaller and smaller and smaller until eventually you are stacked head
over heart, heart over pelvis. Sweet, bring the palms together,
Anjuli Mudra at the heart. Sit up nice and tall once again. Inhale in deeply. Nice, cleansing
breath out through the mouth as you relax the shoulders down. Thank you so much
for sharing your time and your energy with me
and with Benji here today. I hope this
practice serves you well. Bookmark it, favorite it,
make a mental note. Practice this regularly
so we can keep you healthy and happy and feeling good. Love you guys, take good care. Namaste. (upbeat music)
How LSD and shrooms could help treat anxiety, addiction and depression
It was the most peaceful, joyous, incredible, life changing experience I’ve ever had in my life. There were scary parts, foreboding parts … I always knew there was beautiful and joy …
It was the most peaceful, joyous, incredible,
life changing experience I’ve ever had in my life. There were scary parts, foreboding
parts … I always knew there was beautiful and joy and peace on the other side of it.
It was freeing, it was really freeing. This is Alana. She’s describing what she
felt after she took a dose of this stuff — psilocybin. It’s a naturally occurring psychedelic compound,
the kind you find in magic mushrooms. But she wasn’t tripping in a dorm room or
at Woodstock — it actually wasn’t recreational at all.
If anything became unreal or I was feeling nervous or not in touch with reality, I would
squeeze his hand and he would squeeze mine back just to reassure me that I was okay and
everything was alright. It was part of a controlled medical test to
see if psychedelics could be useful in helping people quit cigarettes. Alana had been smoking
for 37 years before her session with psilocybin, and she hasn’t had a cigarette since. Research on psychedelics for medical use is
preliminary. Most studies suffer from really small sample sizes. That’s partly because the
federal government lists LSD and psilocybin as Schedule 1 drugs. So researchers face extra
red tape, and funding is really hard to come by. Vox writer German Lopez reviewed dozens of
studies that have been done. He found that psychedelics show promise for treating addiction,
OCD, anxiety, and in some cases, depression. One small study of 15 smokers found that 80
percent were able to abstain from smoking for six months after a psilocybin treatment.
In a pilot study of 12 advanced cancer patients suffering from end-of-life anxiety, participants
who took psilocybin generally showed lower scores on a test of depression.
And smaller study suggested psilocybin treatment could also help people with alcohol dependence
cut back on their drinking days. We don’t have all the answers as to what
exactly these treatments are doing in the brain. But they seem to work by providing
a meaningful, even mystical experience that leads to lasting changes in a patient’s life. The issues that I talked about, or thought about, or went into during my experience were transformative in the sense that I got to look at them through a different lens. I know this sounds weird, I feel like I have more connections in my brain that I couldn’t
access before That feeling that Alana is describing is actually
pretty spot-on. When you take LSD your brain looks something
like this. You can actually see a higher degree of connectivity
between various parts of the brain, it’s not limited to the visual cortex. This communication inside the brain helps explain visual hallucinations — and the researchers argue that it could
also explain why psychedelics can help people overcome serious mental issues.
They wrote that you can think of psychiatric disorders as the brain being “entrenched
in pathology.” Harmful patterns become automated and hard to change, and that’s what can make
things like anxiety, addiction and depression very hard to treat. That’s Albert Garcia-Romeu, he’s a Johns Hopkins researcher who worked on studies of
of psilocybin and smoking addiction, like the one that Alana’s involved with. He says that when participants take psychedelics, One of the big remaining questions here is
how long these benefits actually last after just the one-time treatment.
A review of research on LSD-assisted psychotherapy and alcoholism found no statistically significant
benefits after 12 months. And a recent study on psilocybin and depression
found that benefits significantly dropped off after three months. And of course are some big risks to using
psychedelic drugs. It’s hard to predict a patient’s reaction
and some might actually endanger themselves. Those predisposed to psychotic conditions
are especially at risk for having a traumatic experience while on the drug.
It’s difficult to draw solid conclusions from the existing studies.
But there’s more than enough promise here to merit further research and further funding
for that research. As Matthew Johnson of Johns Hopkins said,
“These are among the most debilitating and costly disorders known to humankind.” For
some people, no existing treatments help. But psychedelics might. One thing you might still be wondering is why so much of this research is so new, when we’ve known when we’ve known about psychedelics for thousands of years. Well since these drugs are so old, they can’t be patented, which means that pharmaceutical companies don’t really have any incentive to fund any research into them. So that really leaves it up to governments and private contributors to fund all these studies. And there actually was a lot of research done into these drugs in the 50s and 60s, but there was a big enough backlash to the abuse of psychedelics in that period, especially around events like Woodstock, that funding really dried up, and research stopped. And that’s why it’s only now that we see this research happening, with private, not government contributions.
Generalized anxiety disorder (GAD) – causes, symptoms & treatment
Say you’ve got a huge presentation in front of all your colleagues; you’re nervous, you’ve got quite a bit of stress leading up to the presentation. That stress is completely normal, …
Say you’ve got a huge presentation in front
of all your colleagues; you’re nervous, you’ve got quite a bit of stress leading
up to the presentation. That stress is completely normal, and really—probably useful in certain
situations since it can make you more alert and careful. After the presentation’s over
you feel the stress start to fade away, right? Well…for 3% of the population, the stress
doesn’t go away, and maybe that stress isn’t even brought on by a specific event and is
always just sort of always there. Either way, at this point it’s considered to be anxiety.
That anxiety might even get worse over time, and causes things like chest pains or nightmares. Sometimes the anxiety’s so severe that it
causes someone to be anxious about leaving the house or doing everyday things, like going
to work or school. This anxiety may be a sign of Generalized Anxiety Disorder, sometimes
shortened to GAD. GAD’s characterized by excessive, persistent, and unreasonable anxiety
about everyday things, like money, family, work, and relationships; even sometimes the
thought of getting through the day causes anxiety. If the anxiety’s persistent, then
it doesn’t seem to go away, if it’s excessive, it’s usually more than someone else might
feel, and if it’s unreasonable, they probably shouldn’t have a reason to feel anxious
about it. People who have GAD might even understand
that their anxieties are excessive and unreasonable, but they feel it’s out of their control
and don’t quite know how to stop it. People with severe GAD might be completely debilitated
and have trouble with the simplest daily activities, or they might be only mildly affected and
be able to function socially and hold down a job. Sometimes the feelings might worsen
or improve over time. In addition to having feelings of worries
and anxiety, other symptoms include edginess and restlessness, difficulty concentrating
or feeling like the mind just goes blank, and also irritability. These psychological
symptoms can also lead to physical manifestations of symptoms like digestive problems from eating
more or eating less. They might also have muscle aches and soreness from carrying tension
in their muscles. Finally difficulty sleeping is a really common symptom that can have a
serious impact on physical well-being, since the body’s not resting and can lead to issues
of chronic fatigue. Although the decision that someone’s worry
is excessive and unreasonable has a subjective quality, diagnosing GAD is aided by the diagnostic
and statistical manual of mental disorders, or DSM-V, this manual gives a list of criteria
to meet in order to be diagnosed with GAD. First, the excessive worry and anxiety has
to have been present for more days than not over the course of 6 months. In other words,
a person should have the symptoms of excess or unreasonable worry on 90 or more days out
of 180 days. Generally, people can’t quantify or track their feelings in that way, so again,
this is meant to offer a general guideline, right? Okay second—the person finds it hard
to control their anxiety, meaning that they have a hard time calming themselves or “self-soothing”
to help themselves regain control over their feelings. Third, an adult must have three
or more of the symptoms listed previously. In children though, typically defined as “school-age”,
so between 6 and 18 years old, only one symptom is needed for the diagnosis of GAD. Another
criteria is that the anxiety causes impairment in important daily activities like school
or work. For example, they might miss deadlines or find it difficult to even go to work because
of their symptoms. Fifth, the symptoms are not attributable to the physiologic effects
of a drugs or medication, or due to a medical condition like hyperthyroidism which creates
an excess of thyroid hormone, which can sometimes cause symptoms of anxiety and worry. Finally,
their anxiety isn’t better explained by another mental disorder like social phobia
or panic disorder. Just like a lot of mental disorders, it’s
unclear exactly why some individuals develop generalized anxiety disorder, but it’s thought
to be a combination of genetic and environmental factors, as it seems to run in families. It
also has been shown to be twice as prevalent in females than in males. Treating GAD, like many mental disorders,
may involve psychotherapy, medication, or a combination of the two. If it’s psychotherapy,
cognitive behavior therapy has been effective since it teaches the patient to think and
behave in different ways, and react differently to situations that would usually causes anxiety
and worry. Medications like benzodiazepines or antidepressants might be prescribed as
well, benzodiazepines are a type of psychoactive drug that have a relaxing and calming effect.
Antidepressants might also be prescribed, like selective serotonin reuptake inhibitors,
or SSRIs, which regulate the serotonin levels in the brain and help elevate mood. Even though
both medications and cognitive behavior therapy have similar effectiveness in the short-term,
cognitive behavior therapy has major advantages over medication in the long term, due to unwanted
effects of the medications like tolerance, dependence, and withdrawal.
How To Care For Vinyl Wraps – 2016 BMW M4 – Chemical Guys Car Care
Hey guys, welcome back to the Detail Garage. Today we have this 2016 BMW M4 in the shop, as you can see it has this cool gray finish which is actually …
Hey guys, welcome back to the Detail Garage. Today we have this 2016 BMW M4 in the shop,
as you can see it has this cool gray finish which is actually a wrap. So we’re going to be showing you how to properly
wash as well as maintain this without harming the finish. Before we do that we’re going to jump on the
dirtiest area which is the wheels. Brake dust and all kinds of grime collects
on the wheel because as you drive all kinds of things attract to the surface. It’s actually degrading the finish so we are
going to get that off there without scratching it. You can’t even tell these wheels are actually
glossy because of the amount of grime that is on the surface. All that brake dust gives it a cloudy look. We’re going to start by rinsing it down, then
using three Gerbil Wheel Brushes to safely pull off the filth without scratching. Then we can move to the tire and remove old
dressings using the Stiffy Blue Brush, it will remove anything else that was on the
surface as well as embedded grime. Any kind of old dressing will sling on to
the paint job and that is how you get these little black specs. We’re going to rinse it off then get started
with the detailing process. So now that we have rinsed it down using the
Fire Hose Nozzle, it has taken care of the loose brake dust. Now we can get into the more intricate areas
like the barrel, spokes and lug nuts using the Gerbil Wheel Brushes. I’ll start by placing a Dirt Trap in the bucket,
this bucket has fresh water for rinsing to prevent bring the dirt back on to the wheel. We’ll agitate anything that is on the surface
using Sticky Citrus Wheel Gel to emulsify and trap particles on the surface so we won’t
scratch it. It creates lubricating bubbles that loosen
and soften contamination so we can easily take it off and get this wheel looking its
best. You can use this on any kind of wheel finish
like OEM, matte wheels, chrome and so on to make them look great. Starting with the biggest Wheel Gerbil at
the top of the wheel, getting all the way to the back of the wheel down the barrel for
a perfectly clean wheel. By using the biggest Wheel Gerbil it has taken
care of the brake dust that is all the way in the back of the barrel. Now we’re moving on to the medium size Wheel
Gerbil so we can get all the crevices and spokes when the bigger brush wouldn’t fit. Spraying it for added lubrication and cleaning
power. Slide it in between the spoke, this is an
area where a lot of brake dust collects and over time it can start to pitting and deteriorating
the finish so we are going to get all that out of there. You can see that the medium size Gerbil does
an amazing job getting between the spokes and it works great for cleaning in between
the caliper and inner barrel. This is an area that is hard to get bigger
brushes in and around. So now using the last Gerbil Brush which is
the smallest. Again spraying it with Sticky Citrus Wheel
Gel for more lubrication and cleaning power because anything that’s on there is corrosive
and car scratch so you’ll want as much lubrication as possible. It works well for cleaning lug nuts, emblems
and for detailing the caliper because it is hard to get a brush behind the spokes. So now you have more mobility to get all the
around without scratching the painted finish of the caliper. Now this wheel is looking really good, we’re
going to move on to the final step of cleaning the tire using the Stiffy Brush. I’ll spray down the tire one last time with
Sticky Wheel Gel to loosen up any grime that was on the rim as well as old dressings. Scrubbing all the way around the tire to get
it looking its best. Now this tire is looking really good. We’re going to finish it off by rinsing it
down and then we’ll take it inside to continue the rest of the detailing process. If you don’t believe me just take a look at
this bucket, it’s disgusting. So we’re moving right along with the detail
on this BMW. As I mentioned earlier this is a vinyl wrap,
so I’m going to show you the proper techniques and products you’ll need to keep it looking
fresh. This is just a protective layer of vinyl that
is very thin so sun rays beating down on it or things that harm the vinyl like tree sap
and bird droppings can cause it to peel and fade. Using Wrap Detailer and spraying it right
on the surface will rejuvenate the wrap as well as protect it. You can use this on the vinyl wrap, glass
and wheels. It’s a quick detail spray that picks up loose
dirt, bird droppings, sap and water drops to bring back the pristine finish. You can see it has a light layer of dust on
there. Although this car looks really clean there
are actually things still on the surface that can harm the finish. We’re going to get it all cleaned off and
protected, then move to the interior. Real quickly I wanted to mention the towel
we’re using, this is the Happy Ending Towel. It is a very plush towel, vinyl is very sensitive
so we want a very soft towel that will remove anything on the surface without scratching. I’m going to finish off the rest of the vehicle
and then we can jump on the interior. The last step of our detailing process is
cleaning the interior of this BMW. Starting with a vacuum to pick up the filth
and debris then clean and protect the leather. Whenever you use a vacuum on leather, make
sure the edges aren’t sharp. Typically when you drop your vacuum the plastic
edges will scrape making the plastic sharp and if you run this across the leather it
can cause scratches or tears which are hard to repair or replace. So be very careful when you are working on
sensitive surfaces such as leather. We’re going to vacuum the seats, carpet and
finish up the rest of the cleaning process. Alright guys we have made it to the end of
the detail on this BMW. To wrap it up we’re going to hit all the leather
surfaces in the interior using Leather Quick Detailer. This cleans and protects in one step. Just spray it on the surface or on a towel to control
over spray and then wipe down the leather and buff off any excess. That is going to add a UV protective coating
that also resists stains and solar rays from damaging the finish. I’m going to finish this off, in the meantime you guys can head over to our website chemicalguys.com. If you like this car or this video be sure
to give it a thumbs up. Don’t forget to drop a comment below if there
is something you want to see or want more information about. We’ll see you guys next time right here in
the Detail Garage.
Introduction to Point of Care Ultrasound (POCUS) – Basics
okay well we’re going to dive right into ultrasound physics and instrumentation and while this may not be the most exciting topic to start off with I assure you it is …
okay well we’re going to dive right into
ultrasound physics and instrumentation and while this may not be the most
exciting topic to start off with I assure you it is foundational to apply
ultrasound clinically and even though physics is in the title of the
presentation do not let that frighten you in classic med cram style we will
break down the concepts so that they are easy for you to understand in this
course we are going to define ultrasound we will discuss basic ultrasound physics
will touch on ultrasound biosafety and the lraa principle we will discover
different ultrasound transducers and their applications we will look at
ultrasound orientation and common ultrasound terminology will explore
ultrasound neurology or the different knobs and controls that you need to know
on the ultrasound machine we will look at the ultrasound modes will discuss
ultrasound artifacts and we’ll finish up with a step-by-step guide on how to
perform an exam on a patient well let’s start off by defining ultrasound and if
this line represents all of the possible audio frequencies that exist then a
portion of those frequencies are audible or those that can be heard by the human
ear and this is said to be 20 Hertz to 20,000 Hertz well then everything below
the hearing threshold is said to be infra sound or subsonic then everything
above the hearing threshold is said to be ultra sound so ultrasound is simply
sound waves that are above the hearing threshold in diagnostic medical
ultrasound the frequency ranges typically are one to twenty plus
megahertz that are being used before we dive into ultrasound physics I want to
briefly explain how an ultrasound machine works and while you may not be
familiar with an ultrasound machine you’re likely familiar with the speaker
and since they both generate sound wave it provides a good example the speaker
uses electrical energy in the electrical waves that travel through the speaker
cable cause the speaker to pump in and out this generates sound waves in the
air which are then heard by the human ear well similarly the ultrasound
machine uses electrical energy the electrical waves generated by the
ultrasound machine traveled down the transducer cable into the transducer and
the transducer produces sound waves but in this case some of these sound waves
reflect off of the patient’s tissues and are transmitted back to the transducer
the transducer then at this point converts the sound waves that it’s
receiving back into electrical energy which is then processed to form a visual
image on the ultrasound machine so let’s look at this another way
you have your ultrasound transducer in your patient the ultrasound transducer
generates a sound wave it’s transmitted through the patient’s tissues reflected
back to the transducer and then those returning sound waves or those returning
echoes are processed to form a single scan line now there’s a few components
of the scan line that I’d like to discuss in one is depth depth is a
function of distance to the ultrasound machine meaning the longer that it takes
to return to the ultrasound machine means it had to penetrate deeper into
the tissues and the ultrasound machine knows to place those returning echoes
deep in the scan line conversely the more shallow that the ultrasound wave
must penetrate and reflect back the less time it takes to return and therefore
the ultrasound machine knows to place that more shallow on the scan line the
second component that you’ll notice is the brightness and think of the
brightness as the volume of the returning echo if you will or the
intensity of the returning echo the louder the returning echo
the brighter it will appear the quieter the returnee echo the less bright it
will appear so a more intense returning echo will appear brighter in a less
intense returning echo will appear darker
well this same process happens again to form another scan line and this repeats
in a sequential fashion to form a 2d image now on this 2d image you can pick
out the individual scan lines and that’s because it’s an old ultrasound image of
a fetal skull but in modern ultrasound images you will no longer be able to see
the individual scan lines that will appear as a homogeneous 2d image but the
image is still generated in the same fashion so now that we understand how an
ultrasound machine works let’s return to our discussion of ultrasound physics as
we touched on before as the speaker pumps in and out it generates sound
waves well how does it really do this well as it pumps out it compresses air
molecules and these areas of highly compressed air molecules are called
compressions and as it goes back in creates this
vacuum effect and there is areas of low pressure called rare fractions and with
this alternating in-out movement it creates alternating compressions in
rare fractions and for this course we will illustrate compressions as a sound
wave like this in the space in between them as rare fractions so for us to
discuss the characteristics of a sound wave it’s much easier to depict the
compressions as Peaks on a sine wave in the rare fractions as troughs on a sine
wave although we understand that a sound wave is not a sine leaf but the first
characteristic of a sound wave we want to discuss is the wavelength in the
wavelength is the distance between a peak and a peak and a trough in a trough
and similarly the time between a peak and a peak in a trough in a trough is
called a period so wavelength is a function of distance and period as a
function of time the next characteristics will see is the
amplitude an amplitude is the height of the peak of a sound wave or how high
pressure the compression is this is the loudness or in the intensity of the
sound so the higher the amplitude the louder the sound or the more intense the
sound the lower the amplitude the less intense the sound is and then lastly
we’ll look at frequency and frequency is how many sound waves travel past a
certain point in a certain period of time and frequency is measured in Hertz
and Hertz are cycles per second so the more waves that pass a given point in a
second the higher the frequency the less sound waves that pass a given point in a
second the lower the frequency okay well to make sure we understand these
characteristics of sound waves I want to do a few examples so we’re going to
compare these various sound waves and if we compare the top wave to the middle
wave will notice the wavelength of the top wave is longer compared with the
wavelength of the middle wave therefore since the wavelength is longer the
frequency is going to be lower and therefore the pitch of this sound wave
on top will be lower than the middle wave if we look at the amplitude the
amplitude of the top wave compared to the middle wave however is lower
therefore the volume or the amplitude of the top wave will be quieter than the
volume or amplitude of the middle sound wave in the bottom wave has an even
longer wavelength therefore a lower frequency and it also has a lower
amplitude than both the above waves so therefore it will be lower in quieter
and if you look at this you’ll notice a key concept that frequency is inversely
proportional to wavelength meaning the bigger the wavelength the lower the
frequency and the smaller the wavelength the higher the frequency so what does
this have to do with diagnostic medical ultrasound well it primarily boils down
to these concepts of resolution versus penetration now resolution simply is how
pretty your picture is how defined in detail the ultrasound image is
penetration simply is how deep the ultrasound wave is able to penetrate
into the patient’s body and therefore generate an image and these things are
primarily a function of frequency see as you increase the frequency you improve
the resolution and as you decrease the frequency you decrease the resolution or
the resolution gets poorer now the converse is true of penetration as you
increase the frequency you decrease your ability to penetrate into the tissue and
the opposite is true where you decrease your frequency you actually increase
your ability to penetrate into the tissue now if this doesn’t make sense or
seem to abstract let me give you two illustrations what is in photography in
the age of smartphones all having cameras many people know that the
cameras resolution is rated in megapixels so the higher the megapixel
on your camera the better that resolution is or the prettier the
picture will be but as you know if the object you are trying to take a picture
of is a far distance away your resolution decreases you’ve all zoomed
in on your smartphone when the object is far away and the picture gets all grainy
and you can’t see it as well it’s because the better the resolution is
when the object is closer to you or another illustration
be in music you’ve all driven by a stadium concert and when you’re half a
mile a mile away from that concert you can actually hear the bass you don’t
hear any of the rest of the music you just hear those very low frequencies
it’s because those low frequencies those large wavelengths can travel a long
distance they can penetrate very well but they’re not well defined you can’t
hear the detail of the low frequency where if you were to go into that
stadium and put your ear right up against the speaker it would be the high
frequencies that pierce your ear because they’re very well defined but they
cannot travel a far distance all right well that wraps up how an ultrasound
machine works in the basics of ultrasound physics next we will look at
the interactions of ultrasound in tissue